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low dose naltrexone
1 Replies
joeboy - June 20

any one tried it or have any info GREATLY appreciated

 

Fantod - June 20

Low-dose naltrexone (LDN), where naltrexone is used in doses approximately much lower than those used for drug/alcohol rehabilitation purposes, is being used as an "off-label" treatment for certain immunologically related disorders such as Crohn's disease, multiple sclerosis, fibromyalgia, and some cancers.

Naltrexone is an opioid receptor antagonist, meaning that it binds to the same cell receptors that opioid drugs bind to. Opioids include natural compounds such as endorphins (responsible for the basic sense of one's mental well-being and contendedness, feeling of reward and the "runner's high"). The body produces its own natural opioids, and there are also synthetic and semi-synthetic maufactured drugs known as opioids, such as morphine, methadone, buprenorphine (Suboxone/Subutex), fentanyl, oxycodone (OxyContin, Percocet), hydrocodone (Vicodin, Lortab, Hycodan), codeine, and diacetylmorphine/heroin. Naltrexone is FDA approved for use in high doses (at least 50 mg) to counteract the effects of drug and alcohol dependence. Low-dose naltrexone has not been approved as an 'off label' treatment by the U.S. FDA.

Naltrexone hydrochloride has the chemical name of 17-(cyclopropylmethyl)-4,5?-epo
xy-3,14-dihydroxymorphinan-6-on
e
hydrochloride and a molecular weight of 377.86.[1] It is a white crystalline compound, soluble in water.

To-date, there has been recent, significant clinical research activity into the use of LDN as treatment for several (non-drug and alcohol dependence) disorders.

I just read a book called "Honest Medicine" which also talks about LDN. You can use Google to find the website associated with the book. There should be more information about LDN there. Take care.

 

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